Organic Chemistry

Prospects of graduates

The graduate of the PhD program in Organic Chemistry understands in depth the theories, principles, methods and logical procedures of chemistry studied. He/she is a specialist chemist in organic chemistry and modern stereoselective synthesis. Graduates of the third level of the undergraduate degree in organic chemistry are able to carry out challenging multi-step organic syntheses, separate and purify products, identify their structure using spectral methods, and independently carry out research in organic chemistry. Graduates can independently and creatively use the specialized conceptual apparatus and methods of these scientific disciplines, which are a consequence of the interdisciplinary nature of chemistry and the requirements of professional practice. They are proficient in working with databases and the basics of molecular modelling.

The student is also able to assist in the teaching of specialized chemistry courses in higher education and to conduct research independently. The acquired theoretical and practical knowledge allows him to manage technical staff, graduate students in chemistry and take responsibility for complex solutions. Graduates can apply themselves in a wide range of organic-chemical applications with links to medicinal, pharmaceutical chemistry and biochemistry, materials and environmental chemistry, applying advanced methods and techniques of scientific research.

The interdisciplinary nature of organic chemistry gives graduates of this field of study great opportunities for postdoctoral fellowships in a variety of specialties on a global scale.

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Conditions of admission

successful completion of the entrance exam

Additional information

Organic Chemistry: Unsaturated hydrocarbons, alkenes, electron-donor properties of alkenes, reactions, addition of halogens, halogen-hydrocarbons, addition of sulfuric acids, addition of organic acids, hydroboration, addition of carbon monoxide, radical addition reactions, hydration, addition of alcohols, addition of organometallic compounds, oxidation, epoxidation, addition of ozone, hydroxylation, dienes to polyenes, reactions, isomerization, salt formation, pericyclic reactions, electrocyclic reactions, cycloaddition reactions, cycloalkenes. Alkynes. Aromatic hydrocarbons, properties, benzenoid hydrocarbons, nomenclature. Electrophilic substitution reactions, nitration, sulfonation, halogenation, alkylation, acylation, orienting effect of substituents, mechanism and energy diagram, radical addition and substitution nucleophilic reactions, oxidation, non-benzenoid aromatic hydrocarbons. Halogen derivatives, reactivity and reactions, nucleophilic substitution reactions, influence of alkyl group on reaction mechanism, mechanism of SN1 and SN2 reactions, nucleophilic substitution of haloalkanes by anions, Hydrolysis and alcoholysis, substitution by C, N, O, S anions, molecular shifts, elimination reactions, E1 and E2 reactions, substitution reactions of halogenarenes, reactions of halogenarenes with metals. Hydroxyderivatives. Reactions of hydroxyderivatives as acids and bases. Tautomerism. Elimination and oxidation reactions, diols their properties and reactions. Dehydration of diols. Pinacoline shear. Substitution electrophilic and oxidation reactions of phenols. Sigmatropic shear. Carbonyl compounds. Aldehydes and ketones, addition nucleophilic, condensation, oxidation and reduction reactions. Addition reactions to conjugated carbonyl groups. C-anion reactions of carbonyl compounds. Aldol condensation and related reactions. Cross aldol condensation. Alkylation and acylation of carbonyl compounds. Methods of preparation of carbonyl compounds. Benzyl shear. Carboxylic acids - characteristics, nomenclature, physicochemical properties and reactions. Functional and substituent derivatives of carboxylic acids - acyl halides, anhydrides, esters and amides. Reactions of ethyl acetoacetate. Ketogenic and acid-forming cleavages. Halogen, hydroxycarboxylic acids, lactones, amino acids. Organic nitrogen compounds. Amines, diazo compounds, nitro and nitroso compounds, hydroxylamines, oxime and hydrazines. Beckman's slip. Heterocyclic compounds. Five-membered heterocyclic compounds: furan, pyrrole, thiophene, pyrazole, imidazole, thiazole, benzofuran, indole and thionaphthene. Six-membered heterocyclic compounds: pyridine, quinoline, isoquinoline, acridine, pyridazine, pyrimazine, pyrimidine, pyrazine, purine and pteridineStructure and reactivity of organic compounds:Bonds in organic compounds, ionic and covalent bonding, bond energy, atomic orbitals, molecular orbital theory, hybridization, donor-acceptor bonding, hydrogen bonding, bond polarity, polarizability, stereochemistry, isomerism, optical activity, chirality, configuration, enantiomers, diastereoisomers, racemates. Reactions of organic compounds, chemical equilibrium, thermodynamics of reactions, heat of reaction, entropy, enthalpy, free activation energy, transition states, rate of reaction, reaction equilibrium, thermodynamically and kinetically controlled reactions, mechanisms of organic reactions, homolytic and heterolytic bond cleavage, intermediates, synergistic and multistep reactions, catalysis, effect of solvent, types of reactions. Ultraviolet and visible spectroscopy. Infrared spectroscopy. Raman spectroscopy Mass spectroscopy. Nuclear magnetic resonance spectroscopy. One-dimensional (1D) 1H NMR spectroscopy. Two-dimensional (2D) NMR spectroscopy. Principles and measurement techniques. Presentation of spectra. Correlated 2D NMR spectra (H,H-COSY, H,C-COSY, TOCSY, NOESY, INADEQUATE, long range correlation). Kinetics of organic reactions. Rate constant and kinetic equation. Methods used in monitoring reaction rates. Procedures used in determining kinetic equations and rate constants. Acid-base catalysis. Linear free energy relationships.

Form of entrance exam


  • Apply the application for study

    01.03.2024 - 31.05.2024

  • Performance of the entrance exam

    17.06.2024 - 28.06.2024

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  • CV
  • verified copy of the degree for applicant of other universities
  • photocopy of the Diploma Supplement to candidates from other universities

Annual tuition fees
Standard length of study: cost free

The fee for admission procedure
application form: 50 €
E-application form: 40 €

Billing information

Bank: Treasury. Bank code: 8180

Account number: SK 28 8180 0000 0070 0007 8491

Variable symbol: 2996

Constant symbol: 0308

Specific symbol: birth number without slash

Recipient message: name and surname of the applicant

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Detail of the study program

The first three years of your studies could be funded by a scholarship of up to €9,000. More information

Detail of the study program


0911 154 882
0910 288 664
037 / 6414881
037 / 6414890
(7.30 - 15.30 h.)


Responsibility for content: RNDr. Iveta Sováková –
Last update: 30.11.2023 09:45

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